New biological imaging possibilities with free electron lasers

15th September 2009 Biochemistry Lecture Theatre, Sanger
Building, Tennis Court Road, University of Cambridge

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The Road Show aims to explain the potential (and limitations) of free electron lasers for new imaging methods in the biological sciences. Proof of principle experiments have been carried out at FLASH, Hamburg, which have confirmed that images can be obtained within 20 fs before the specimen is destroyed. The Linac Coherent Light Source (LCLS) facility, Stanford, will become operational for users in the Autumn 2009 and will allow extension of these methods with shorter wavelength X-rays to the possible imaging of biological macromolecules. The New Light Source Committee (chair Jon Marangos, Imperial College) has been considering the implications of the new technology for UK science. In particular the committee sees potential for cellular imaging for intact specimens at ~1 nm resolution and in the THz region for dynamic studies and imaging for medical applications. The NLS committee would welcome discussion and input from the scientific community on these proposals.


14.00 - 14.05 Welcome and Introduction (Louise Johnson)

14.05 - 14.45 Flash Imaging (Henry Chapman, FLASH, DESY, Hamburg)

14.45 - 15.20 Possibilities for flash imaging in the life sciences
(Louise Johnson, Diamond Light Source and University of Oxford)


15.20 - 1600 The New Light Source project
(Jon Marangos, Imperial College and Chair of New Light Source Project)


16.00 - 16.40 THz imaging and pump probe experiments
(Peter Weightman, University of Liverpool)


16.40 Close